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BPC-157 / TB-500 (Wolverine Blend)

BPC-157 / TB-500 (Wolverine Blend)

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Research with confidence, supported by clear compound information

For Research Use Only
Lyophilized Peptide
Technical Specifications
Published Research References

Compound Information

Technical profiles and key research areas

BPC-157 PROFILE

Body Protection Compound-157

A synthetic 15-amino-acid peptide sequence studied in preclinical models involving cellular protection and tissue-response pathways.

Key research focus
Cellular protection Tissue response Peptide stability
Compound Type Synthetic pentadecapeptide
CAS Number 137525-51-0
Molecular Weight 1,419.5 g/mol
Amino Acids 15
View PubChem Record
TB-500 / THYMOSIN β4 PROFILE

Thymosin Beta-4 Research

Thymosin β4 is a naturally occurring 43-amino-acid peptide studied for its relationship with actin regulation and cellular migration.

Key research focus
Actin regulation Cell migration Tissue remodeling
Compound Type Thymosin β4-related peptide
Reference Peptide Thymosin beta-4
Molecular Weight Approximately 4.9 kDa
Amino Acids 43
View PubMed Research
BLEND RESEARCH OVERVIEW

Why Study the Combination?

The two peptide profiles are studied together because they are associated with different but potentially complementary biological pathways.

01
BPC-157 Cellular protection and vascular-response pathways
02
THYMOSIN β4 Actin regulation and cell-migration pathways
03
SHARED RESEARCH AREA Inflammatory signaling and tissue remodeling
Format Dual-peptide blend
Evidence Primarily preclinical
Use Laboratory research only

Research remains preliminary and does not establish clinical safety or efficacy.

View Research Review

BPC-157 + TB-500 RESEARCH LIBRARY

Sources & References

Peer-reviewed research and scientific resources related to BPC-157 and thymosin beta-4.

01CLINICAL REVIEW

GLOBALRPH

BPC-157 and TB-500: Background, Indications, Efficacy, and Safety

2025 Clinical review

McAuley D

View source
02SYSTEMATIC REVIEW

HSS JOURNAL · PUBMED CENTRAL

Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review

2025 PMCID: PMC12313605

Vasireddi N, Hahamyan H, Salata MJ, et al.

View source
03SCIENTIFIC REVIEW

EXPERT OPINION ON BIOLOGICAL THERAPY

Thymosin β4: A Multi-Functional Regenerative Peptide. Basic Properties and Clinical Applications

2012 PMID: 22074294

Goldstein AL, Hannappel E, Sosne G, et al.

View source
04CLINICAL STUDY

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

A Randomized, Placebo-Controlled, Single and Multiple Dose Study of Intravenous Thymosin Beta4 in Healthy Volunteers

2010 PMID: 20536472

Ruff D, Crockford D, Girardi G, Zhang Y

View source
05WOUND RESEARCH

JOURNAL OF INVESTIGATIVE DERMATOLOGY

Thymosin Beta4 Accelerates Wound Healing

1999 PMID: 10469335

Malinda KM, Sidhu GS, Mani H, et al.

View source
06TENDON RESEARCH

JOURNAL OF APPLIED PHYSIOLOGY

The Promoting Effect of Pentadecapeptide BPC 157 on Tendon Healing Involves Tendon Outgrowth, Cell Survival, and Cell Migration

2011 DOI: 10.1152/japplphysiol.00945.2010

Chang CH, Tsai WC, Lin MS, Hsu YH, et al.

View source
07VASCULAR RESEARCH

SCIENTIFIC REPORTS · NATURE

Modulatory Effects of BPC 157 on Vasomotor Tone and the Src-Cav-1-eNOS Signaling Pathway in Rats

2020 PMID: 33046803

Hsieh MJ, Lee CH, Chueh HY, et al.

View source
08PRECLINICAL SAFETY

REGULATORY TOXICOLOGY AND PHARMACOLOGY

Preclinical Safety Evaluation of Body Protective Compound-157, a Potential Drug for Treating Various Wounds

2020 PMID: 32334036

Xu C, Sun L, Ren F, et al.

View source
09CARDIAC RESEARCH

NATURE

Thymosin Beta4 Activates Integrin-Linked Kinase and Promotes Cardiac Cell Migration, Survival and Cardiac Repair

2004 PMID: 15565145

Bock-Marquette I, Saxena A, White MD, et al.

View source
10TENDON RESEARCH

GROWTH HORMONE & IGF RESEARCH

BPC-157 Enhances Growth Hormone Receptor Expression in Injured Tendon Tissue

2018 DOI: 10.1016/j.ghir.2018.02.001

Staresinic M, Sebecic B, et al.

View source
11SCIENTIFIC REVIEW

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Progress on the Function and Application of Thymosin β4

2021 PMCID: PMC8724243

Xing Y, et al.

View source
12PHASE 1 TRIAL

CLINICALTRIALS.GOV

PCO-02 – Safety and Pharmacokinetics Trial

2015 NCT02637284

Phase 1 study registry

View source
13LITERATURE INDEX

COMBINED LITERATURE

BPC-157 and TB-500 Combined Research Base

2025 PubMed literature index

Research articles and citations

View source

External references are provided for scientific and educational context. BPC-157 + TB-500 is supplied strictly for laboratory research and is not intended for human or veterinary use.

Use & Compliance

Important Research Notice

Please review the following research-use conditions before purchasing, handling, or referencing this compound.

Research use only notice stating not for human consumption
Primary restriction Not for human consumption.
01

Intended Research Use

This product is sold exclusively for laboratory research, analytical testing, and educational purposes. It is not intended for human or veterinary use, consumption, administration, diagnosis, treatment, mitigation, cure, or prevention of disease.

02

Information Disclaimer

Any clinical trial data, technical information, or research findings presented on this page are provided for educational reference only. They should not be interpreted as medical advice, treatment guidance, or product claims.

03

Purchaser Responsibility

By purchasing this product, you confirm that you are a qualified researcher and will use it responsibly and in accordance with all applicable laws and regulations.

Discover more in our FAQ

1. What is the BPC-157 + TB-500 Blend?

The BPC-157 + TB-500 Blend combines two research peptides in one lyophilized formulation. BPC-157 is a synthetic 15-amino-acid peptide, while TB-500 is associated with thymosin beta-4 research. The blend is intended for laboratory studies examining their distinct and potentially complementary biological pathways.